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Poliomyelitis eradication
A public health effort to eliminate all cases of poliomyelitis (polio) infection around the world, begun in 1988 and led by the World Health Organization (WHO), UNICEF and the Rotary Foundation, has reduced the number of annual diagnosed cases from the hundreds of thousands to 291 in 2012. This represents a 99.9% reduction, but in 2013 and 2014 there has been an bounce back in some countries towards more cases. Of the three types of polio, the last recorded wild case of type 2 was in 1999. The last recorded case of type 3 was on 11 November 2012. All reported cases since 11 November 2012 have been of type 1. If polio is the next disease to be successfully eradicated, this will represent only the third time this has ever been achieved, after smallpox and rinderpest. The goal of eradicating polio worldwide has attracted international and media attention, but since 2001 progress has been erratic in reducing the number of cases, which has led to getting rid of the last 1% being described as "like trying to squeeze Jell-O to death". However, in 2011 incidence rates of the disease were dramatically reduced, and with large reduction again in 2012, hopes for eliminating polio have been rekindled. India is the latest country to successfully stop transmission of polio—with its last reported case in 2011. Only 2 countries remain where the disease is endemic—Afghanistan and Pakistan. Nigeria's last reported wild case was 24 July 2014, and the WHO declared it no longer to have endemic wild polio on 25 September 2015. The number of cases reported in the first nine months of 2015 has been about a quarter of the rate of the preceding three years.〔
== Factors influencing eradication of polio ==
Eradication of polio has been defined in various ways—as elimination of the occurrence of poliomyelitis even in the absence of human intervention, as extinction of poliovirus, such that the infectious agent no longer exists in nature or in the laboratory, as control of an infection to the point at which transmission of the disease ceased within a specified area,〔 and as reduction of the worldwide incidence of poliomyelitis to zero as a result of deliberate efforts, and requiring no further control measures.
In theory, if the right tools were available, it would be possible to eradicate all infectious diseases that reside only in a human host. In reality there are distinct biological features of the organisms and technical factors of dealing with them that make their potential eradicability more or less likely.〔General: Centers for Disease Control and Prevention. Global disease elimination and eradication as public health strategies. MMWR 1999;48(Suppl). Specific: Centers for Disease Control and Prevention. (The Principles of Disease Elimination and Eradication. ) In: Global disease elimination and eradication as public health strategies. MMWR 1999;48(Suppl).〕 Three indicators, however, are considered of primary importance in determining the likelihood of successful eradication: that effective interventional tools are available to interrupt transmission of the agent, such as a vaccine; that diagnostic tools, with sufficient sensitivity and specificity, be available to detect infections that can lead to transmission of the disease; and that humans are required for the life-cycle of the agent, which has no other vertebrate reservoir and cannot amplify in the environment.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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